• Programmed death ligand PD L expression is

  2019-04-24

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• In the phase AZURE trial women were randomly assigned

  2019-04-24

  

  In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic AL 8697 every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, for a total of 5 years

• Any abnormality causing a loss of function in the

  2019-04-24

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• Table shows the results of achieving ECV for atrial

  2019-04-24

  

  Table 3 shows the results of achieving ECV for atrial arrhythmia in this study. There was no significant between-group difference in the number of ECV attempts or the prevalence of successful ECV. The number of days to ECV in OAC-naïve patients was significantly less in the NOACs group (n=72) compar

• The district specific estimates of

  2019-04-24

  

  The district-specific estimates of effectiveness (figure 1) include infections averted in all population subgroups over the first 4 years, even for districts without surveys of men who have sex with men and the general population, and the state-level and overall proportion of infections averted acro

• In their analysis the investigators did not include common

  2019-04-24

  

  In their analysis, the investigators did not include common causes of CKD in sub-Saharan Africa other than HIV, diabetes, and hypertension—notable omissions were chronic glomerulonephritis and use of herbal or traditional treatments. Also, communicable diseases might contribute substantially to CKD

• A key component of the Emergency Nutrition Response was

  2019-04-24

  

  A key component of the Emergency Nutrition Response was the implementation of a Child Nutrition Week to deliver a package of essential nutrition services for children younger than 5 years and their mothers before the onset of the monsoon rains. The Child Nutrition Week built on the experience of chi

• Pero m s all del folclore

  2019-04-24

  

  Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber

• The diagnosis of PTC based on

  2019-04-24

  

  The diagnosis of PTC, based on the Modified Dandy Criteria, is made when a patient exhibits an elevated LP opening pressure above 25cm H20 with normal CSF composition and radiologic findings, and no other explanation for the rise in intracranial pressure [6]. The most common presenting symptom occur

• Introduction Acute acalculous cholecystitis ACC is defined a

  2019-04-24

  

  Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl

• membrane transport Evidence supporting the benefit of dexraz

  2019-04-23

  

  Evidence supporting the benefit of dexrazoxane as cardioprotective therapy in adults with acute leukemia are scant [11]. However, there is a significant need for cardioprotective therapy, particularly in older individuals with preexisting cardiovascular disorders and/or prior anthracycline exposure,

• br Community based bundled health interventions are complex

  2019-04-23

  

  Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and

• Cancer stem cells are capable of differentiation and self re

  2019-04-23

  

  Cancer stem aminopeptidase are capable of differentiation and self-renewal. In 1994, CSCs were described for the first time. Hematological malignance is the best evidence to support the existence CSCs. TPC (tumor Propagating cell) is the other phrase that has been used for cancer stem cells. CSCs p

• Sea una domesticaci n retraducci n simplificaci n o reversi

  2019-04-23

  

  Sea una domesticación, retraducción, simplificación o reversión del francés al español del Caribe, lo cierto es que estos traductores se benefician del discurso literario utilizado por Chateaubriand ya que se muestra como un discurso flexible, capaz de aceptar cambios, desvíos y apropiaciones. En At

• En esta l nea los editorialistas sin la intenci n

  2019-04-23

  

  En esta línea, los editorialistas sin la intención de convertirse en los aguafiestas del advenimiento de la República, criticaban las afirmaciones sobre las bondades de la intervención. “Cuba está mucho peor que en 1899. Los gobiernos militares dieron mayor interés ddhCTP la política que al desarrol

13113 records 869/875 page Previous Next First page 上5页 866867868869870 下5页 Last page