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With the availability of vaccines
2019-05-08
With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th
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A second methodological issue concerns the
2019-05-08
A second methodological issue concerns the accuracy of the exposure measurement. Without accurate measurement, different methods for calculating attributable risk that are equivalent in theory are not guaranteed to give compatible results in practice. Previous experience with carcinogenic infections
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The clinical presentation of patients with CIED
2019-05-08
The clinical presentation of patients with CIED pocket infection and those with endovascular infection can vary, but once the diagnosis is made, the management is similar and involves removal of all hardware along with antibiotic therapy [2,7,8,15]. Conservative managements with spleen tyrosine kina
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A substantial body of evidence linking inflammation
2019-05-08
A substantial body of evidence linking inflammation to the pathophysiology of a broad spectrum of cardiovascular diseases, including coronary artery disease, diabetes mellitus, and hypertension, has been developed [8–11]. Similarly, the hypothesis that inflammatory processes are involved in the path
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Si se rescata de estas
2019-05-08
Si se rescata de estas afirmaciones, en primer término, la pretensión crítica realista como fundamento de su propuesta literaria, algunos de los cambios en su entorno cultural cobran relevancia para contextualizar su interés por la ironización de la realidad dentro de la heterogeneidad de su obra. C
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We discussed in our report the potential to
2019-05-08
We discussed in our report the potential to improve vaccine acceptance and increase demand for OPV by engaging people within communities to deliver health education. Our analysis focused on all reported sources of health education within a community—ie, not only traditional leaders but also the loca
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Muy a pesar de que ambos
2019-05-08
Muy retinoid x receptor pesar de que ambos documentos de la Congregación para la Doctrina de la Fe citaban repetidamente el documento conclusivo de la reunión de la conferencia del celam en Puebla -que no la de Medellín—, la postura de Ratzinger evidenció el criterio hegemónico enunciado desde una p
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The mechanism leading to the
2019-05-08
The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo
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Complete surgical resection of the
2019-05-08
Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com
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According to Weitzman classification patients
2019-05-08
According to Weitzman classification [43] 15 patients had a single ONJ lesion (4A) and 9 patients had multiple lesions (4B) or a “multifocal” lesion (Table 2). Six patients interrupted the treatment with O3 gas application for disease progression (five patients) and for fear of an experimental ther
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A year old woman presented
2019-05-08
A 54-year-old woman presented to our clinic with palpitation and shortness of breath. Six years previously, she underwent successful catheter ablation for focal atrial tachycardia (AT) originating from the HOBt of the right atrial appendage and right side of the fossa ovalis. However, AT originatin
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cetp inhibitor Efforts to estimate the global
2019-05-07
Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me
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Villoro cuestiona la forma incorrecta en que es
2019-05-07
Villoro cuestiona la forma incorrecta en que es presentada la relación entre estos derechos como dos sujetos confrontados, en tanto que opina que no existe un sujeto colectivo en el mismo sentido que lo es el sujeto individual, sólo éste es intencional, el colectivo no es un ente que exista sin la p
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A Irmandade da Santa Casa de Miseric
2019-05-07
A Irmandade da Santa Casa de Misericórdia de São Paulo é formada por membros da sociedade que passam protease inhibitor ser chamados de Irmãos. Desses, são escolhidos os que compõem a Mesa Administrativa, a qual escolhe a diretoria, nomeados como provedor e superintendente. Em geral, são profissiona
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In the phase AZURE trial women were randomly assigned to
2019-05-07
In the phase 3 AZURE trial, 3360 women were randomly assigned to receive standard adjuvant systemic treatment alone (control group) or with 4mg intravenous zoledronic MM-102 every 3–4 weeks for 6 doses, then every 3 months for 8 doses, followed by every 6 months for 5 doses, for a total of 5 years o
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