• br Role of catecholamines in HIV associated neuroinflammatio

  2022-06-10

  

  Role of catecholamines in HIV-associated neuroinflammation Concluding remarks However, more research is needed to determine the precise mechanisms responsible for the immunomodulatory effects of catecholamines, including the involvement of specific receptors and signaling pathways in immune ce

• atp citrate lyase Management of HIV treatment with HIV PIs

  2022-06-10

  

  Management of HIV-1 treatment with HIV PIs can be complicated due to wide inter-patient variability in atp citrate lyase levels. In certain scenarios, therapeutic drug monitoring (TDM) has been recommended as a useful approach to individualize therapy for HIV-infected patients [[9], [10], [11], [12

• The finding of histamine action on ASICs

  2022-06-10

  

  The finding of histamine action on ASICs also raises the question about possible action of other histamine receptor ligands. In the present work we selected several compounds and performed electrophysiological testing of their action on recombinant homomeric ASIC1a and ASIC2a. Nα-methylhistamine is

• Interestingly in vivo infusion and uptake of Ang II

  2022-06-10

  

  Interestingly, in vivo infusion and uptake of Ang II in intact mice indicated that multiligand endocytic receptor megalin has at least some role in the uptake of Ang II and the downstream signaling process in proximal tubule acetaminophen paracetamol (PTCs) in vivo [173]. Earlier in vivo studies sho

• As a result of the capability of

  2022-06-10

  

  As a result of the capability of modulating the dynamic changes and rearrangement of cytoskeletons, the Rho GTPases, in which RhoA, Cdc42 and Rac1 are best-characterized, have been highlighted as significant contributors for orchestrating neuronal development (Duman et al., 2015, Heasman and Ridley,

• G protein coupled receptors GPCRs constitute a large

  2022-06-10

  

  G-protein coupled receptors (GPCRs) constitute a large family of 7 trans-membrane-spanning proteins that activate internal signal transduction cascades through binding to different ligands including neurotransmitters, peptides, and lipids [7]. This family of receptors has therapeutic potentials in t

• br Redox regulation in the brain Reactive

  2022-06-09

  

  Redox regulation in the brain Reactive oxygen species are generated in aurora kinase pathway by the mitochondrial respiratory chain, which occurs on the inner mitochondrial membrane (Murphy, 2009, Jensen, 1966, Dickinson and Chang, 2011). Interestingly, although most cancer cells are thought to p

• Due to the requirement of high end

  2022-06-09

  

  Due to the requirement of high-end methods such as total internal reflection fluorescence (TIRF) microscopy to visualize lipid rafts, isolation procedures are employed to study the protein content of lipid rafts [29]. The different methods utilized to isolated lipid rafts and other low density micro

• So far the functional significance of GluR A and GluR

  2022-06-09

  

  So far, the functional significance of GluR-A and GluR-B in synaptic plasticity has been best studied in the context of long-term potentiation of synaptic transmission in vitro in the hippocampus and the regulation of synaptic strength in paradigms underlying activity-dependent learning in vivo Taka

• Young et al described the role of

  2022-06-09

  

  Young et al. [40] described the role of adenine monophosphate-activated protein kinase (AMPK) in the translocation of GLUT4 in the heart. The AMPK is activated during muscle contraction [74] by converting AMP to ATP. The adenosine analog, 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), is a c

• Sodium Nitroprusside australia br Introduction The glucagon

  2022-06-09

  

  Introduction The glucagon receptor (GCGR) is a G-protein-coupled receptor expressed mainly in the liver and kidney. Upon glucagon binding, it activates the stimulatory G protein (Gs) and increases cAMP level, subsequently transducing glucagon signaling involved in glucose, amino acids and lipid m

• br Competing interests br Acknowledgements br Introduction F

  2022-06-09

  

  Competing interests Acknowledgements Introduction - Factors Regulating Glucose Tolerance Strictly speaking, the incretin effect refers to the amplification of insulin secretion, which occurs when carbenicillin is taken in orally as compared to infused intravenously [1]. Normally, the insul

• caspofungin Besides its established insulinotropic actions G

  2022-06-09

  

  Besides its established insulinotropic actions, GIP has been shown to possess other direct beneficial effects on the beta cell, including stimulation of growth, differentiation, proliferation and survival.21, 22, 23 It has also been shown to stimulate proinsulin gene transcription and translation. M

• In terms of stimulation oxytocin dopamine noradrenaline adre

  2022-06-09

  

  In terms of stimulation, oxytocin, dopamine, noradrenaline, adrenaline and glucagon have all been reported to increase ghrelin secretion (Mundinger et al., 2006, Iwakura et al., 2011, de la Cour et al., 2007, Gagnon and Anini, 2013). Stimulatory effects on ghrelin secretion have also been observed w

• This study compared PMS ascorbate and t

  2022-06-09

  

  This study compared PMS+ascorbate and t-BHP in terms of their effects on the volume-dependent parameters of normal human RBCs. Incubation with both oxidative systems resulted in the RBC density and osmotic resistance distribution shifts. Clotrimazole or Са2+ added into the medium, as well as high ex

11092 records 114/740 page Previous Next First page 上5页 111112113114115 下5页 Last page